Sharma, A.; Kamble, S. H.; Leon, F.; Chear, N. J.; King, T. I.;Berthold, E. C.; Ramanathan, S.; McCurdy, C. R.; Avery, B. A., Simultaneous quantification of ten key Kratom alkaloids in Mitragyna speciosa leaf extracts and commercial products by ultra-performance liquid chromatography-tandem mass spectrometry. Drug Test Anal 2019, 11 (8), 1162-1171.
Berthold, E. C.; Yang, R.; Sharma, A.; Kamble, S. H.; Kanumuri, S. R.; King, T. I.; Popa, R.; Freeman, J. H.; Brym, Z. T.; Avery, B. A.; McCurdy, C. R., Regulatory sampling of industrial hemp plant samples (Cannabis sativa L.) using UPLC-MS/MS method for detection and quantification of twelve cannabinoids. J Cannabis Res 2020, 2 (1), 42.
Kamble, S. H.; Leon, F.; King, T. I.;Berthold, E. C.; Lopera-Londono, C.; Siva Rama Raju, K.; Hampson, A. J.; Sharma, A.; Avery, B. A.; McMahon, L. R.; McCurdy, C. R., Metabolism of a Kratom Alkaloid Metabolite in Human Plasma Increases Its Opioid Potency and Efficacy. ACS Pharmacol Transl Sci 2020, 3 (6), 1063-1068.
Kamble, S. H.; Sharma, A.; King, T. I.;Berthold, E. C.; Leon, F.; Meyer, P. K. L.; Kanumuri, S. R. R.; McMahon, L. R.; McCurdy, C. R.; Avery, B. A., Exploration of cytochrome P450 inhibition mediated drug-drug interaction potential of kratom alkaloids. Toxicol Lett 2020, 319, 148-154.
King, T. I.; Sharma, A.; Kamble, S. H.; Leon, F.;Berthold, E. C.; Popa, R.; Cerlati, O.; Prentice, B. M.; McMahon, L. R.; McCurdy, C. R.; Avery, B. A., Bioanalytical method development and validation of corynantheidine, a kratom alkaloid, using UPLC-MS/MS, and its application to preclinical pharmacokinetic studies. J Pharm Biomed Anal 2020, 180, 113019.
Maxwell, E. A.; King, T. I.; Kamble, S. H.; Raju, K. S. R.;Berthold, E. C.; Leon, F.; Avery, B. A.; McMahon, L. R.; McCurdy, C. R.; Sharma, A., Pharmacokinetics and Safety of Mitragynine in Beagle Dogs. Planta Med 2020, 86 (17), 1278-1285.
Popa, R.; Kamble, S. H.; Kanumuri, R. S.; King, T. I.;Berthold, E. C.; Intagliata, S.; Sharma, A.; McCurdy, C. R., Bioanalytical method development and pharmacokinetics of MCI-92, a sigma-1 receptor ligand. J Pharm Biomed Anal 2020, 191, 113610.
Yang, R.;Berthold, E. C.; McCurdy, C. R.; da Silva Benevenute, S.; Brym, Z. T.; Freeman, J. H., Development of Cannabinoids in Flowers of Industrial Hemp (Cannabis sativa L.): A Pilot Study. J Agric Food Chem 2020, 68 (22), 6058-6064.
Berthold, E. C.; Kamble, S. H.; Raju, K. S.; King, T. I.; Popa, R.; Sharma, A.; Leon, F.; Avery, B. A.; McMahon, L. R.; McCurdy, C. R., Preclinical pharmacokinetic study of speciociliatine, a kratom alkaloid, in rats using an UPLC-MS/MS method. J Pharm Biomed Anal 2021, 194, 113778.
Kamble, S. H.;Berthold, E. C.; King, T. I.; Raju Kanumuri, S. R.; Popa, R.; Herting, J. R.; Leon, F.; Sharma, A.; McMahon, L. R.; Avery, B. A.; McCurdy, C. R., Pharmacokinetics of Eleven Kratom Alkaloids Following an Oral Dose of Either Traditional or Commercial Kratom Products in Rats. J Nat Prod 2021, 84 (4), 1104-1112.
Leon, F.; Obeng, S.; Mottinelli, M.; Chen, Y.; King, T. I.;Berthold, E. C.; Kamble, S. H.; Restrepo, L. F.; Patel, A.; Gamez-Jimenez, L. R.; Lopera-Londono, C.; Hiranita, T.; Sharma, A.; Hampson, A. J.; Canal, C. E.; McMahon, L. R.; McCurdy, C. R., Activity of Mitragyna speciosa ("Kratom") Alkaloids at Serotonin Receptors. J Med Chem 2021, 64 (18), 13510-13523.
Maxwell, E. A.; King, T. I.; Kamble, S. H.; Raju, K. S. R.;Berthold, E. C.; Leon, F.; Hampson, A.; McMahon, L. R.; McCurdy, C. R.; Sharma, A., Oral Pharmacokinetics in Beagle Dogs of the Mitragynine Metabolite, 7-Hydroxymitragynine. Eur J Drug Metab Pharmacokinet 2021, 46 (3), 459-463.
Berthold, E. C.; Kamble, S. H.; Raju, K. S.; Kuntz, M. A.; Senetra, A. S.; Mottinelli, M.; Leon, F.; Restrepo, L. F.; Patel, A.; Ho, N. P.; Hiranita, T.; Sharma, A.; McMahon, L. R.; McCurdy, C. R., The Lack of Contribution of 7-Hydroxymitragynine to the Antinociceptive Effects of Mitragynine in Mice: A Pharmacokinetic and Pharmacodynamic Study. Drug Metab Dispos 2022, 50 (2), 158-167.
Kamble, S. H.;Berthold, E. C.; Kanumuri, S. R. R.; King, T. I.; Kuntz, M. A.; Leon, F.; Mottinelli, M.; McMahon, L. R.; McCurdy, C. R.; Sharma, A., Metabolism of Speciociliatine, an Overlooked Kratom Alkaloid for its Potential Pharmacological Effects. AAPS J 2022, 24 (5), 86.
Popa, R.; Kamble, S. H.; Kanumuri, R. S.; King, T. I.;Berthold, E. C.; Intagliata, S.; Sharma, A.; McCurdy, C. R., UPLC-MS/MS method for the quantification of MCI-77, a novel sigma-1 receptor ligand, and its application to pharmacokinetic studies. J Chromatogr B Analyt Technol Biomed Life Sci 2022, 1196, 123187.
Berthold, E. C.; Kamble, S. H.; Kanumuri, S. R. R.; Kuntz, M. A.; Senetra, A. S.; Chiang, Y. H.; McMahon, L. R.; McCurdy, C. R.; Sharma, A., Comparative Pharmacokinetics of Commercially Available Cannabidiol Isolate, Broad-Spectrum, and Full-Spectrum Products. Eur J Drug Metab Pharmacokinet 2023.
Duong, H.; Pearson, B.; Anderson, S.;Berthold, E.; Kjelgren, R., Variation in Hydric Response of Two Industrial Hemp Varieties (Cannabis sativa) to Induced Water Stress. Horticulturae 2023, 9 (4), 431.
Kamble, S. H.; Obeng, S.; León, F.; Restrepo, L. F.; King, T. I.;Berthold, E. C.; Kanumuri, S. R. R.; Gamez-Jimenez, L. R.; Pallares, V. L.; Patel, A.; Ho, N. P.; Hampson, A.; McCurdy, C. R.; McMahon, L. R.; Wilkerson, J. L.; Sharma, A.; Hiranita, T., Pharmacokinetic and Pharmacodynamic Consequences of CYP3A Inhibition on Mitragynine Metabolism in Rats. J Pharmacol Exp Ther 2023.
Penman, S. L.;Berthold, E. C.; Mihalkovic, A.; Hammond, N.; McCurdy, C. R.; Blum, K.; Eiden, R. D.; Sharma, A.; Thanos, P., Vaporized Delta-9-tetrahydrocannabinol Inhalation in Female Sprague Dawley Rats: A Pharmacokinetic and Behavioral Assessment. Curr Pharm Des 2023.
Penman, S. L.; Roeder, N. M.;Berthold, E. C.; Senetra, A. S.; Marion, M.; Richardson, B. J.; White, O.; Fearby, N. L.; McCurdy, C. R.; Hamilton, J.; Sharma, A.; Thanos, P. K., FABP5 is important for cognitive function and is an important regulator of the physiological effects and pharmacokinetics of acute Δ9 tetrahydrocannabinol inhalation in mice. Pharmacol Biochem Behav 2023, 231, 173633.